Cyclic analog

Octreotide

Octreotide is an eight-amino-acid cyclic analog of somatostatin used clinically for hormone-secreting tumors and related indications.

By The Peptides Codex Editorial TeamReviewed July 10, 2026

Length

8 aa

Class

Cyclic analog

Function

Somatostatin receptor agonist

Context

Acromegaly, neuroendocrine tumors (approved)

Longer-acting cyclic analog of somatostatin.

Part of the Foundational & therapeutic peptides cluster

Overview

Octreotide is an eight-amino-acid cyclic analog of somatostatin used clinically for hormone-secreting tumors and related indications.

Source & context

Biological / chemical source: Synthetic analog

Primary research or clinical context: Acromegaly, neuroendocrine tumors (approved)

Analog design

Shortening and cyclizing somatostatin improved stability and receptor subtype preference — classic peptide medicinal chemistry.

FAQ about Octreotide

What is Octreotide?+

Octreotide is an eight-amino-acid cyclic analog of somatostatin used clinically for hormone-secreting tumors and related indications.

Is Octreotide an approved medicine?+

Octreotide: Acromegaly, neuroendocrine tumors (approved). Always follow licensed medical guidance for approved products.

What is the typical length of Octreotide?+

Octreotide is commonly described as approximately 8 amino acids (Cyclic analog).

Related peptides

Cyclosporin A

Cyclic

Cyclosporin A is a cyclic non-ribosomal peptide immunosuppressant used in transplant medicine — a landmark natural product peptide drug.

Somatostatin

Hormone

Somatostatin is a 14-residue inhibitory peptide hormone regulating growth hormone and multiple gut/pancreatic hormones.

SNAP-8

Cosmetic peptide

SNAP-8 (acetyl octapeptide-3) is a cosmetic peptide marketed in skincare science as a SNARE-complex–related topical ingredient. It is distinct from injectable research peptides.

Follistatin-344

Glycoprotein / activin-binding protein isoform

Follistatin-344 (FS-344) is the 344-amino-acid precursor isoform of follistatin, an activin-binding protein encoded by the FST gene. It antagonizes TGF-β superfamily ligands such as myostatin and activin, making it a focus of muscle-biology research. It is not an approved therapeutic in Canada.

References & further reading

Disclaimer: Educational content only. Not medical advice. Not instructions for human use. Research peptides and unapproved products may be restricted or illegal to market for human consumption in your jurisdiction. Consult qualified professionals and applicable law.

You might also like: All peptides · Atlas · Research · Tools

Cite this: Peptides Codex — Octreotide educational profile.

Tip: Use browser print (Ctrl/Cmd + P) for a clean PDF of this page.