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Cosmetic peptide

SNAP-8

SNAP-8 (acetyl octapeptide-3) is a cosmetic peptide marketed in skincare science as a SNARE-complex–related topical ingredient. It is distinct from injectable research peptides.

By The Peptides Codex Editorial TeamIndividual review date not recorded

Page data last changed: . Chemistry registry snapshot: . Registry refreshes and identity assessments are separate from scientific content review.

Length
8 aa
Class
Cosmetic peptide
Function
SNARE-related cosmetic peptide used in topical anti-wrinkle research marketing
Context
Cosmetic / topical ingredient discussions

Captures beauty/cosmetic peptide search traffic adjacent to research peptides.

Also known as: acetyl octapeptide-3 · SNAP8

Part of the Cosmetic & skin peptides cluster

Overview

SNAP-8 (acetyl octapeptide-3) is a cosmetic peptide marketed in skincare science as a SNARE-complex–related topical ingredient. It is distinct from injectable research peptides.

Source & context

Biological / chemical source: Synthetic octapeptide

Primary research or clinical context: Cosmetic / topical ingredient discussions

Cosmetic vs research injectables

Topical cosmetic peptides and injectable research chemicals have different mechanisms, exposure routes, and regulatory contexts. Evidence for one product or route does not establish the safety or effects of another.

Structure & chemistry

Molecular identity & reference confidence

Source-supported reference

Reference values are taken from the cited molecular record or curated profile. A database match is not independent laboratory verification; modifications, counter-ions, and formulations can change the measured mass.

Molecular form
SNAP-8 (source record; form not independently established)
Species
Not established by this molecular identity audit
Termini (N / C)
Not specified / Not specified

Average reference mass

Reference policy updated: 2026-10-05

Molecular formula
C42H72N16O15S
Average reference mass
≈ 1,073.2
Identifiers

Chemistry values: PubChem · fetched 2026-10-01.

Concentration math

SNAP-8 — reconstitution calculator

Enter how much peptide is in the vial and how much diluent (e.g. bacteriostatic water) is added. The tool returns the resulting solution concentration — and, for any amount you type, the volume it corresponds to. This is educational arithmetic, not a dosing recommendation.

Reference form: SNAP-8 (source record; form not independently established)Average reference mass: 1,073.2 Da

Syringe graduation
Solution concentration
5 mg/mL5,000 mcg/mL
mcg

Enter an amount to see the volume it corresponds to.

Educational concentration mathematics only. This tool does not recommend a dose, amount, or protocol, and nothing here is medical advice. Many peptides are not authorized by Health Canada for human use — see our reconstitution and bacteriostatic-water guides for context.

Open the SNAP-8 calculator on its own page →

FAQ about SNAP-8

What is SNAP-8?+

SNAP-8 (acetyl octapeptide-3) is a cosmetic peptide marketed in skincare science as a SNARE-complex–related topical ingredient. It is distinct from injectable research peptides.

What Canadian product status is recorded for SNAP-8?+

Canadian product status for SNAP-8 has not been verified in this profile. No verified record here does not mean no authorization exists. Status depends on the product, formulation and use; consult Health Canada's product records.

What is the typical length of SNAP-8?+

SNAP-8 is commonly described as approximately 8 amino acids (Cosmetic peptide).

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Octreotide
Somatostatin analogue (approved medicine)
Octreotide is a cyclic eight-amino-acid synthetic analogue of somatostatin (C49H66N10O10S2, ≈1,019 Da) with a D-phenylalanine at position 1, a D-tryptophan at position 4 and a disulfide bridge between its two cysteines. It suppresses growth hormone, thyrotropin and a range of pancreatic and gut hormones. Approved for acromegaly, TSH-secreting pituitary tumours and neuroendocrine tumours, it is available as injection, long-acting depot and — since 2020 — an oral capsule, and radiolabelled forms image somatostatin-receptor-positive tumours.
Somatostatin
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Somatostatin is a 14-residue inhibitory peptide hormone regulating growth hormone and multiple gut/pancreatic hormones.
Matrixyl
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Matrixyl is the trade name of palmitoyl pentapeptide-4 (Pal-KTTKS), a lipidated pentapeptide used in anti-wrinkle skincare. The C16 palmitoyl tail lets it self-assemble into nanotapes and stimulates collagen production in human dermal fibroblasts in a concentration-dependent way (Jones et al., Molecular Pharmaceutics 2013). It is a cosmetic ingredient, not a drug, and controlled human data on the peptide itself are scarce.

References & further reading

  1. 1.PubChem — compound summary for Acetyl octapeptide-3 / SNAP-8 (CID 71587832)
Disclaimer: Educational content only. Not medical advice. Not instructions for human use. Research peptides and unapproved products may be restricted or illegal to market for human consumption in your jurisdiction. Consult qualified professionals and applicable law.
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