Peptides Codex
Home
Hormone

Somatostatin

Somatostatin is a 14-residue inhibitory peptide hormone regulating growth hormone and multiple gut/pancreatic hormones.

By The Peptides Codex Editorial TeamReviewed July 10, 2026
Length
14 aa
Class
Hormone
Function
Inhibits GH, insulin, glucagon
Context
Basis for analogs in neuroendocrine disease

Broad inhibitory peptide; analogs like octreotide are clinic staples.

Part of the Foundational & therapeutic peptides cluster

Overview

Somatostatin is a 14-residue inhibitory peptide hormone regulating growth hormone and multiple gut/pancreatic hormones.

Source & context

Biological / chemical source: Hypothalamus, pancreas

Primary research or clinical context: Basis for analogs in neuroendocrine disease

Clinical analogs

Short half-life of native somatostatin drove development of octreotide, lanreotide, and pasireotide — a major peptide drug class.

Sequence

One-letter sequence commonly cited for Somatostatin (educational; isoforms and modifications may differ):

AGCKNFFWKTFTSC

AGCKNFFWKTFTSC

Analyze sequences in the playground →

FAQ about Somatostatin

What is Somatostatin?+

Somatostatin is a 14-residue inhibitory peptide hormone regulating growth hormone and multiple gut/pancreatic hormones.

Is Somatostatin an approved medicine?+

Somatostatin is discussed here as a research / educational topic. Basis for analogs in neuroendocrine disease. This is not medical advice.

What is the typical length of Somatostatin?+

Somatostatin is commonly described as approximately 14 amino acids (Hormone).

Related peptides

References & further reading

  1. 1.Wikipedia — Somatostatin
  2. 2.PubChem — compound summary for Somatostatin (CID 16129706)
Disclaimer: Educational content only. Not medical advice. Not instructions for human use. Research peptides and unapproved products may be restricted or illegal to market for human consumption in your jurisdiction. Consult qualified professionals and applicable law.
You might also like: All peptides · Atlas · Research · Tools
Cite this: Peptides Codex — Somatostatin educational profile.
Tip: Use browser print (Ctrl/Cmd + P) for a clean PDF of this page.