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Research / clinical peptide

SS-31

SS-31 (elamipretide) is a mitochondria-targeting tetrapeptide studied for effects on mitochondrial membranes and bioenergetics in experimental and clinical research programs.

By The Peptides Codex Editorial TeamReviewed July 10, 2026
Length
4 aa
Class
Research / clinical peptide
Function
Mitochondria-targeted tetrapeptide
Context
Clinical development history for mitochondrial/cardiac indications; research use

Mitochondrial peptide pharmacology — premium educational niche.

Also known as: elamipretide · bendavia · MTP-131

Part of the Foundational & therapeutic peptides cluster

Overview

SS-31 (elamipretide) is a mitochondria-targeting tetrapeptide studied for effects on mitochondrial membranes and bioenergetics in experimental and clinical research programs.

Source & context

Biological / chemical source: Synthetic aromatic-cationic tetrapeptide

Primary research or clinical context: Clinical development history for mitochondrial/cardiac indications; research use

Targeting mitochondria

SS-31 associates with cardiolipin-rich inner mitochondrial membranes in research models — a distinct localization story compared with circulating hormone peptides.

FAQ about SS-31

What is SS-31?+

SS-31 (elamipretide) is a mitochondria-targeting tetrapeptide studied for effects on mitochondrial membranes and bioenergetics in experimental and clinical research programs.

Is SS-31 an approved medicine?+

SS-31 is discussed here as a research / educational topic. Clinical development history for mitochondrial/cardiac indications; research use. This is not medical advice.

What is the typical length of SS-31?+

SS-31 is commonly described as approximately 4 amino acids (Research / clinical peptide).

Related peptides

References & further reading

  1. 1.Wikipedia — Elamipretide
  2. 2.PubChem — compound summary for Elamipretide / SS-31 (CID 11764719)
Disclaimer: Educational content only. Not medical advice. Not instructions for human use. Research peptides and unapproved products may be restricted or illegal to market for human consumption in your jurisdiction. Consult qualified professionals and applicable law.
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Cite this: Peptides Codex — SS-31 educational profile.
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