Cosmetic / research peptide

GHK-Cu

GHK-Cu is a copper complex of the tripeptide glycyl-L-histidyl-L-lysine, extensively discussed in skin biology and cosmetic science literature.

By The Peptides Codex Editorial TeamReviewed July 10, 2026

Length

3 aa

Class

Cosmetic / research peptide

Function

Copper-binding tripeptide studied in skin biology

Context

Widely discussed in cosmetic science; topical formulations common

Bridges cosmetic search demand and peptide chemistry education.

Also known as: copper peptide · GHK copper

Part of the Cosmetic & skin peptides cluster

Overview

GHK-Cu is a copper complex of the tripeptide glycyl-L-histidyl-L-lysine, extensively discussed in skin biology and cosmetic science literature.

Source & context

Biological / chemical source: Endogenous tripeptide complexed with copper(II)

Primary research or clinical context: Widely discussed in cosmetic science; topical formulations common

Chemistry

The GHK sequence binds copper(II) ions. Research explores roles in extracellular matrix remodeling and antioxidant-related pathways in skin models.

Sequence

One-letter sequence commonly cited for GHK-Cu (educational; isoforms and modifications may differ):

GHK

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FAQ about GHK-Cu

What is GHK-Cu?+

GHK-Cu is a copper complex of the tripeptide glycyl-L-histidyl-L-lysine, extensively discussed in skin biology and cosmetic science literature.

Is GHK-Cu an approved medicine?+

GHK-Cu is discussed here as a research / educational topic. Widely discussed in cosmetic science; topical formulations common. This is not medical advice.

What is the typical length of GHK-Cu?+

GHK-Cu is commonly described as approximately 3 amino acids (Cosmetic / research peptide).

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References & further reading

Disclaimer: Educational content only. Not medical advice. Not instructions for human use. Research peptides and unapproved products may be restricted or illegal to market for human consumption in your jurisdiction. Consult qualified professionals and applicable law.

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Cite this: Peptides Codex — GHK-Cu educational profile.

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