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Somatostatin analog

Lanreotide

Lanreotide is a synthetic octapeptide analog of somatostatin that binds the same inhibitory receptors but resists degradation for far longer than the native hormone. It is an approved therapeutic for acromegaly and gastroenteropancreatic neuroendocrine tumors. This page is educational and not medical advice.

By The Peptides Codex Editorial TeamReviewed July 10, 2026
Length
8 aa
Class
Somatostatin analog
Function
Somatostatin receptor agonist
Context
Approved for acromegaly and gastroenteropancreatic neuroendocrine tumors

A long-acting somatostatin octapeptide delivered as an extended-release depot.

Also known as: Somatuline

Part of the Foundational & therapeutic peptides cluster

Overview

Lanreotide is a synthetic octapeptide analog of somatostatin that binds the same inhibitory receptors but resists degradation for far longer than the native hormone. It is an approved therapeutic for acromegaly and gastroenteropancreatic neuroendocrine tumors. This page is educational and not medical advice.

Source & context

Biological / chemical source: Synthetic octapeptide analog of somatostatin

Primary research or clinical context: Approved for acromegaly and gastroenteropancreatic neuroendocrine tumors

Somatostatin mimicry

By activating somatostatin receptor subtypes, lanreotide suppresses growth hormone and multiple gut hormones. Shortening and stabilizing the 14-residue native peptide into a cyclized octapeptide is a textbook example of turning a fleeting hormone into a durable drug.

Depot formulation

Lanreotide is supplied as a supersaturated gel depot that self-assembles under the skin, releasing peptide over several weeks. It sits alongside octreotide and pasireotide in the somatostatin-analog family used to control hormone-secreting tumors.

FAQ about Lanreotide

What is Lanreotide?+

Lanreotide is a synthetic octapeptide analog of somatostatin that binds the same inhibitory receptors but resists degradation for far longer than the native hormone. It is an approved therapeutic for acromegaly and gastroenteropancreatic neuroendocrine tumors. This page is educational and not medical advice.

Is Lanreotide an approved medicine?+

Lanreotide: Approved for acromegaly and gastroenteropancreatic neuroendocrine tumors. Always follow licensed medical guidance for approved products.

What is the typical length of Lanreotide?+

Lanreotide is commonly described as approximately 8 amino acids (Somatostatin analog).

Related peptides

References & further reading

  1. 1.Wikipedia — Lanreotide
  2. 2.PubChem — compound summary for Lanreotide (CID 6918011)
Disclaimer: Educational content only. Not medical advice. Not instructions for human use. Research peptides and unapproved products may be restricted or illegal to market for human consumption in your jurisdiction. Consult qualified professionals and applicable law.
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Cite this: Peptides Codex — Lanreotide educational profile.
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