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GnRH agonist (nonapeptide analog)

Deslorelin

Deslorelin is a synthetic GnRH agonist peptide used primarily in veterinary medicine. As implants such as Suprelorin and Ovuplant, it is applied for reversible chemical castration in dogs and for ovulation timing in mares. This page is educational and is not medical advice.

By The Peptides Codex Editorial TeamReviewed July 10, 2026
Length
9 aa
Class
GnRH agonist (nonapeptide analog)
Function
Gonadotropin-releasing hormone superagonist
Context
Approved for veterinary use (e.g., chemical castration in dogs, ovulation timing in mares); marketed as Suprelorin and Ovuplant

A GnRH superagonist used chiefly in veterinary medicine as a slow-release implant.

Also known as: Suprelorin · Ovuplant · GnRH agonist

Part of the Foundational & therapeutic peptides cluster

Overview

Deslorelin is a synthetic GnRH agonist peptide used primarily in veterinary medicine. As implants such as Suprelorin and Ovuplant, it is applied for reversible chemical castration in dogs and for ovulation timing in mares. This page is educational and is not medical advice.

Source & context

Biological / chemical source: Synthetic GnRH analog

Primary research or clinical context: Approved for veterinary use (e.g., chemical castration in dogs, ovulation timing in mares); marketed as Suprelorin and Ovuplant

Veterinary context

Deslorelin implants provide sustained GnRH receptor activation that, after an initial stimulatory phase, suppresses reproductive hormones. Veterinary applications include managing fertility and behavior in dogs, ferrets, and other species, and controlling reproduction in livestock and companion animals.

Superagonist chemistry

Like other clinical GnRH analogs, deslorelin carries a D-amino-acid substitution at position 6 and a modified C-terminus. These changes raise receptor potency and slow degradation, which is why it is described as a GnRH superagonist.

FAQ about Deslorelin

What is Deslorelin?+

Deslorelin is a synthetic GnRH agonist peptide used primarily in veterinary medicine. As implants such as Suprelorin and Ovuplant, it is applied for reversible chemical castration in dogs and for ovulation timing in mares. This page is educational and is not medical advice.

Is Deslorelin an approved medicine?+

Deslorelin: Approved for veterinary use (e.g., chemical castration in dogs, ovulation timing in mares); marketed as Suprelorin and Ovuplant. Always follow licensed medical guidance for approved products.

What is the typical length of Deslorelin?+

Deslorelin is commonly described as approximately 9 amino acids (GnRH agonist (nonapeptide analog)).

Related peptides

References & further reading

  1. 1.Wikipedia — Deslorelin
  2. 2.PubChem — compound summary for Deslorelin (CID 16133804)
Disclaimer: Educational content only. Not medical advice. Not instructions for human use. Research peptides and unapproved products may be restricted or illegal to market for human consumption in your jurisdiction. Consult qualified professionals and applicable law.
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Cite this: Peptides Codex — Deslorelin educational profile.
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