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Calcitonin

Calcitonin is a 32-amino-acid peptide hormone secreted by thyroid C-cells that helps regulate blood calcium. Salmon calcitonin has been used as an approved medicine in several jurisdictions.

By The Peptides Codex Editorial TeamReviewed July 10, 2026
Length
32 aa
Class
Hormone
Function
Calcium homeostasis regulation
Context
Approved therapeutic (osteoporosis, hypercalcemia in some markets)

Classic calcium-regulating hormone; salmon calcitonin is a therapeutic form.

Part of the Foundational & therapeutic peptides cluster

Overview

Calcitonin is a 32-amino-acid peptide hormone secreted by thyroid C-cells that helps regulate blood calcium. Salmon calcitonin has been used as an approved medicine in several jurisdictions.

Source & context

Biological / chemical source: Thyroid parafollicular (C) cells

Primary research or clinical context: Approved therapeutic (osteoporosis, hypercalcemia in some markets)

Physiology

Calcitonin lowers blood calcium in part by acting on osteoclasts and the kidney, opposing parathyroid hormone. Its disulfide-bridged ring and amidated C-terminus are structural features often highlighted in peptide-hormone education.

Human vs. salmon forms

Salmon calcitonin is more potent and longer-acting than the human sequence and has been formulated as an approved medicine. Any clinical use of calcitonin should follow licensed medical guidance.

FAQ about Calcitonin

What is Calcitonin?+

Calcitonin is a 32-amino-acid peptide hormone secreted by thyroid C-cells that helps regulate blood calcium. Salmon calcitonin has been used as an approved medicine in several jurisdictions.

Is Calcitonin an approved medicine?+

Calcitonin: Approved therapeutic (osteoporosis, hypercalcemia in some markets). Always follow licensed medical guidance for approved products.

What is the typical length of Calcitonin?+

Calcitonin is commonly described as approximately 32 amino acids (Hormone).

Related peptides

References & further reading

  1. 1.Wikipedia — Calcitonin
  2. 2.PubChem — compound summary for Calcitonin (CID 118984394)
Disclaimer: Educational content only. Not medical advice. Not instructions for human use. Research peptides and unapproved products may be restricted or illegal to market for human consumption in your jurisdiction. Consult qualified professionals and applicable law.
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Cite this: Peptides Codex — Calcitonin educational profile.
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