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Somatostatin analog (cyclic octapeptide)

Vapreotide

Vapreotide is a synthetic cyclic octapeptide analog of somatostatin that activates somatostatin receptors. It has been studied and used in some countries for esophageal variceal bleeding related to cirrhosis, though regulatory status varies by market. This page is educational and is not medical advice.

By The Peptides Codex Editorial TeamReviewed July 10, 2026
Length
8 aa
Class
Somatostatin analog (cyclic octapeptide)
Function
Somatostatin receptor agonist
Context
Somatostatin analog studied and used in some countries for esophageal variceal bleeding; regulatory status varies by market

A somatostatin analog in the octreotide/lanreotide family, studied for variceal bleeding.

Also known as: Sanvar · RC-160 · somatostatin analog

Part of the Foundational & therapeutic peptides cluster

Overview

Vapreotide is a synthetic cyclic octapeptide analog of somatostatin that activates somatostatin receptors. It has been studied and used in some countries for esophageal variceal bleeding related to cirrhosis, though regulatory status varies by market. This page is educational and is not medical advice.

Source & context

Biological / chemical source: Synthetic cyclic octapeptide analog of somatostatin

Primary research or clinical context: Somatostatin analog studied and used in some countries for esophageal variceal bleeding; regulatory status varies by market

Somatostatin analog family

Native somatostatin has a very short half-life. Cyclic analogs such as octreotide, lanreotide, and vapreotide were engineered for greater stability and receptor selectivity, expanding the somatostatin pathway into practical therapeutics.

Studied applications

Because somatostatin agonists reduce splanchnic blood flow and inhibit several gut hormones, vapreotide has been examined in gastrointestinal bleeding and other secretory conditions. Availability and approval differ across countries.

FAQ about Vapreotide

What is Vapreotide?+

Vapreotide is a synthetic cyclic octapeptide analog of somatostatin that activates somatostatin receptors. It has been studied and used in some countries for esophageal variceal bleeding related to cirrhosis, though regulatory status varies by market. This page is educational and is not medical advice.

Is Vapreotide an approved medicine?+

Vapreotide is discussed here as a research / educational topic. Somatostatin analog studied and used in some countries for esophageal variceal bleeding; regulatory status varies by market. This is not medical advice.

What is the typical length of Vapreotide?+

Vapreotide is commonly described as approximately 8 amino acids (Somatostatin analog (cyclic octapeptide)).

Related peptides

References & further reading

  1. 1.Wikipedia — Vapreotide
  2. 2.PubChem — compound summary for Vapreotide (CID 23725064)
Disclaimer: Educational content only. Not medical advice. Not instructions for human use. Research peptides and unapproved products may be restricted or illegal to market for human consumption in your jurisdiction. Consult qualified professionals and applicable law.
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Cite this: Peptides Codex — Vapreotide educational profile.
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