A metabolic peptide first described in 2008 that links dietary macronutrient intake to lipid and glucose handling.
Also known as: ENHO · energy homeostasis-associated protein
Part of the Metabolic & GLP-1 peptides cluster
Overview
Adropin is a secreted peptide encoded by the energy homeostasis-associated gene (ENHO) and first described in 2008. Its 76-residue sequence is fully conserved across human, mouse and rat, and it is studied for roles in glucose and lipid metabolism, insulin sensitivity and vascular function. This page is educational and not medical advice.
Source & context
Biological / chemical source: Encoded by the ENHO gene (liver, brain and other tissues)
Primary research or clinical context: Metabolic physiology and biomarker research
Origin and structure
The ENHO gene on chromosome 9 encodes a 76-amino-acid product; the secreted bioactive region corresponds to Adropin34-76. Adropin is expressed in liver, brain, heart and gastrointestinal tissues, and its amino-acid sequence is identical across several mammalian species.
Metabolic research interest
Studies associate circulating adropin with obesity, insulin resistance, dyslipidemia and endothelial function, and it shows circadian variation. It is investigated primarily as a candidate biomarker and signaling molecule in energy-homeostasis research rather than as a therapeutic.
FAQ about Adropin
What is Adropin?+
Adropin is a secreted peptide encoded by the energy homeostasis-associated gene (ENHO) and first described in 2008. Its 76-residue sequence is fully conserved across human, mouse and rat, and it is studied for roles in glucose and lipid metabolism, insulin sensitivity and vascular function. This page is educational and not medical advice.
Is Adropin an approved medicine?+
Adropin is discussed here as a research / educational topic. Metabolic physiology and biomarker research. This is not medical advice.
What is the typical length of Adropin?+
Adropin is commonly described as approximately 76 amino acids (Peptide hormone (hepatokine)).