Page data last changed: . Chemistry registry snapshot: . Registry refreshes and identity assessments are separate from scientific content review.
A cosmetic 'snake-venom' dipeptide modeled on the muscle-nAChR antagonist waglerin-1.
Also known as: dipeptide diaminobutyroyl benzylamide diacetate
Part of the Cosmetic & skin peptides cluster
Overview
SYN-AKE (dipeptide diaminobutyroyl benzylamide diacetate) is a synthetic cosmetic dipeptide designed to mimic waglerin-1, a peptide from the venom of Wagler's pit viper. It is discussed in cosmetic science for the appearance of expression lines and is presented here as a cosmetic ingredient.
Source & context
Biological / chemical source: Synthetic dipeptide mimicking the snake-venom peptide waglerin-1
Primary research or clinical context: Cosmetic ingredient in topical formulations
Waglerin-1 inspiration
Waglerin-1 is a 22-residue snake-venom peptide that antagonizes muscle nicotinic acetylcholine receptors. SYN-AKE is a much smaller synthetic dipeptide built to echo that mechanism in cosmetic-science models, aiming at the appearance of dynamic expression lines rather than any medical effect.
Cosmetic-ingredient framing
SYN-AKE is supplied to formulators as a cosmetic ingredient for topical serums and creams, typically at low percentages. This page describes it as a cosmetic ingredient; it makes no drug, disease-treatment, or muscle-paralysis claim.
Structure & chemistry
Molecular identity & reference confidence
Source-supported reference
Reference values are taken from the cited molecular record or curated profile. A database match is not independent laboratory verification; modifications, counter-ions, and formulations can change the measured mass.
- Molecular form
- SYN-AKE (source record; form not independently established)
- Species
- Not established by this molecular identity audit
- Termini (N / C)
- Not specified / Not specified
Average reference mass
Reference policy updated: 2026-10-05
- PubChem molecular record · 2026-10-01
- Molecular formula
- C23H37N5O7
- Average reference mass
- ≈ 495.6
- PubChem CID: 71465152
- CAS RN: 823202-99-9
- UNII: 38H206R00R
Chemistry values: PubChem · fetched 2026-10-01.
SYN-AKE — reconstitution calculator
Enter how much peptide is in the vial and how much diluent (e.g. bacteriostatic water) is added. The tool returns the resulting solution concentration — and, for any amount you type, the volume it corresponds to. This is educational arithmetic, not a dosing recommendation.
Reference form: SYN-AKE (source record; form not independently established)Average reference mass: 495.6 Da
Enter an amount to see the volume it corresponds to.
Educational concentration mathematics only. This tool does not recommend a dose, amount, or protocol, and nothing here is medical advice. Many peptides are not authorized by Health Canada for human use — see our reconstitution and bacteriostatic-water guides for context.
FAQ about SYN-AKE
What is SYN-AKE?+
SYN-AKE (dipeptide diaminobutyroyl benzylamide diacetate) is a synthetic cosmetic dipeptide designed to mimic waglerin-1, a peptide from the venom of Wagler's pit viper. It is discussed in cosmetic science for the appearance of expression lines and is presented here as a cosmetic ingredient.
What Canadian product status is recorded for SYN-AKE?+
Canadian product status for SYN-AKE has not been verified in this profile. No verified record here does not mean no authorization exists. Status depends on the product, formulation and use; consult Health Canada's product records.
What is the typical length of SYN-AKE?+
SYN-AKE is commonly described as approximately 2 amino acids (Cosmetic ingredient peptide).