A cosmetic 'snake-venom' dipeptide modeled on the muscle-nAChR antagonist waglerin-1.
Also known as: dipeptide diaminobutyroyl benzylamide diacetate
Part of the Cosmetic & skin peptides cluster
Overview
SYN-AKE (dipeptide diaminobutyroyl benzylamide diacetate) is a synthetic cosmetic dipeptide designed to mimic waglerin-1, a peptide from the venom of Wagler's pit viper. It is discussed in cosmetic science for the appearance of expression lines and is presented here as a cosmetic ingredient.
Source & context
Biological / chemical source: Synthetic dipeptide mimicking the snake-venom peptide waglerin-1
Primary research or clinical context: Cosmetic ingredient in topical formulations
Waglerin-1 inspiration
Waglerin-1 is a 22-residue snake-venom peptide that antagonizes muscle nicotinic acetylcholine receptors. SYN-AKE is a much smaller synthetic dipeptide built to echo that mechanism in cosmetic-science models, aiming at the appearance of dynamic expression lines rather than any medical effect.
Cosmetic-ingredient framing
SYN-AKE is supplied to formulators as a cosmetic ingredient for topical serums and creams, typically at low percentages. This page describes it as a cosmetic ingredient; it makes no drug, disease-treatment, or muscle-paralysis claim.
FAQ about SYN-AKE
What is SYN-AKE?+
SYN-AKE (dipeptide diaminobutyroyl benzylamide diacetate) is a synthetic cosmetic dipeptide designed to mimic waglerin-1, a peptide from the venom of Wagler's pit viper. It is discussed in cosmetic science for the appearance of expression lines and is presented here as a cosmetic ingredient.
Is SYN-AKE an approved medicine?+
SYN-AKE is discussed here as a research / educational topic. Cosmetic ingredient in topical formulations. This is not medical advice.
What is the typical length of SYN-AKE?+
SYN-AKE is commonly described as approximately 2 amino acids (Cosmetic ingredient peptide).