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Research peptide

TB-500

TB-500 refers to a synthetic peptide fragment associated with thymosin beta-4 research, studied for effects on cell migration and tissue remodeling in experimental models. It is not an approved medicine.

By The Peptides Codex Editorial TeamReviewed July 10, 2026
Length
7 aa
Class
Research peptide
Function
Studied in cell migration and tissue models
Context
Research compound (not an approved drug)

Often searched alongside BPC-157 as a 'healing stack' research topic.

Also known as: Thymosin Beta-4 fragment · TB500 · Thymosin β4 fragment

Part of the Repair & recovery peptides cluster

Overview

TB-500 refers to a synthetic peptide fragment associated with thymosin beta-4 research, studied for effects on cell migration and tissue remodeling in experimental models. It is not an approved medicine.

Source & context

Biological / chemical source: Synthetic fragment related to thymosin β4 research

Primary research or clinical context: Research compound (not an approved drug)

Relationship to thymosin β4

Full-length thymosin β4 is a 43-residue actin-sequestering peptide. TB-500 is commonly discussed as a shorter research fragment (often the LKKTETQ region) rather than the full endogenous protein.

Research framing

Literature and secondary sources discuss wound-healing and inflammation models. Quality of commercial research materials varies; analytical verification (identity, purity) is a recurring theme in scientific sourcing discussions.

Naming confusion to watch

Vendors may label materials as TB-500, thymosin beta-4, or TB4 interchangeably. Those are not automatically the same analyte. Always match the COA sequence/mass to what the experiment requires.

Compared with BPC-157

The pair is the internet’s default “repair stack,” but the molecules come from different research traditions. Read the BPC-157 vs TB-500 guide for a structured comparison.

Sequence

One-letter sequence commonly cited for TB-500 (educational; isoforms and modifications may differ):

FAQ about TB-500

What is TB-500?+

TB-500 refers to a synthetic peptide fragment associated with thymosin beta-4 research, studied for effects on cell migration and tissue remodeling in experimental models. It is not an approved medicine.

Is TB-500 an approved medicine?+

TB-500 is discussed here as a research / educational topic. Research compound (not an approved drug). This is not medical advice.

What is the typical length of TB-500?+

TB-500 is commonly described as approximately 7 amino acids (Research peptide).

Related peptides

References & further reading

  1. 1.Wikipedia — TB-500
  2. 2.Wikipedia — Thymosin beta-4
  3. 3.PubChem — compound summary for TB-500 (Ac-LKKTETQ, CID 62707662)
Disclaimer: Educational content only. Not medical advice. Not instructions for human use. Research peptides and unapproved products may be restricted or illegal to market for human consumption in your jurisdiction. Consult qualified professionals and applicable law.
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Cite this: Peptides Codex — TB-500 educational profile.
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