Page data last changed: . Chemistry registry snapshot: . Registry refreshes and identity assessments are separate from scientific content review.
Hexarelin-related secretagogue used mainly as a research and anti-doping reference compound.
Part of the Growth hormone & IGF peptides cluster
Overview
Alexamorelin (Ala-His-D-2-methyl-Trp-Ala-Trp-D-Phe-Lys-NH2) is a synthetic growth hormone secretagogue studied in human endocrine research. It shows GH-releasing activity comparable to hexarelin and appears on anti-doping prohibited lists. It is not authorized by Health Canada for therapeutic use.
Source & context
Biological / chemical source: Synthetic heptapeptide GHS
Primary research or clinical context: Research compound (not authorized by Health Canada)
Sequence and mechanism
Alexamorelin is a heptapeptide containing D-amino acids and a 2-methyl-tryptophan residue. Like other GHRP-class peptides it binds the ghrelin (GHS-R1a) receptor to trigger endogenous GH release, and hepatic metabolism can cleave its terminal alanine toward a hexarelin-like metabolite.
Why it is studied
Controlled human studies compared its GH-, prolactin- and ACTH-releasing activity with hexarelin. Because such secretagogues can be misused for performance enhancement, alexamorelin is also tracked in doping-control literature. Coverage here is educational and not a use recommendation.
Structure & chemistry
Molecular identity & reference confidence
Source-supported reference
Reference values are taken from the cited molecular record or curated profile. A database match is not independent laboratory verification; modifications, counter-ions, and formulations can change the measured mass.
- Molecular form
- Alexamorelin (source record; form not independently established)
- Species
- Not established by this molecular identity audit
- Termini (N / C)
- Not specified / Not specified
Average reference mass
Reference policy updated: 2026-10-05
- PubChem molecular record · 2026-10-01
- Molecular formula
- C50H63N13O7
- Average reference mass
- ≈ 958.1
- PubChem CID: 10011122
- CAS RN: 196808-85-2
Chemistry values: PubChem · fetched 2026-10-01.
Alexamorelin — reconstitution calculator
Enter how much peptide is in the vial and how much diluent (e.g. bacteriostatic water) is added. The tool returns the resulting solution concentration — and, for any amount you type, the volume it corresponds to. This is educational arithmetic, not a dosing recommendation.
Reference form: Alexamorelin (source record; form not independently established)Average reference mass: 958.1 Da
Enter an amount to see the volume it corresponds to.
Educational concentration mathematics only. This tool does not recommend a dose, amount, or protocol, and nothing here is medical advice. Many peptides are not authorized by Health Canada for human use — see our reconstitution and bacteriostatic-water guides for context.
FAQ about Alexamorelin
What is Alexamorelin?+
Alexamorelin (Ala-His-D-2-methyl-Trp-Ala-Trp-D-Phe-Lys-NH2) is a synthetic growth hormone secretagogue studied in human endocrine research. It shows GH-releasing activity comparable to hexarelin and appears on anti-doping prohibited lists. It is not authorized by Health Canada for therapeutic use.
What Canadian product status is recorded for Alexamorelin?+
Canadian product status for Alexamorelin has not been verified in this profile. No verified record here does not mean no authorization exists. Status depends on the product, formulation and use; consult Health Canada's product records.
What is the typical length of Alexamorelin?+
Alexamorelin is commonly described as approximately 7 amino acids (Research peptide).
Related peptides
References & further reading
- 1.Pobee et al. (2025). Identification of alexamorelin consumption biomarkers using human hepatocyte incubations and high-resolution mass spectrometry. J Anal Toxicol
- 2.Broglio et al. (2000). Endocrine activities of alexamorelin (Ala-His-d-2-methyl-Trp-Ala-Trp-d-Phe-Lys-NH2), a synthetic GH secretagogue, in humans. Eur J Endocrinol
- 3.European Journal of Endocrinology — Endocrine activities of alexamorelin, a synthetic GH secretagogue, in humans
- 4.Wikipedia — Growth hormone secretagogue